Vitamin B12 Test

Test type
Lab Test

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Collection method

We offer several different options of testing methods. This test is done with Blood. See all tests done with Blood by following the link.

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Persistent fatigue and thyroid issues can often be linked to B12 levels. While a general B12 test may show normal total levels, it’s the active form of B12, constituting only 10-30% of total B12, that’s crucial for your health. GetTested’s Vitamin B12 Test focuses on this active form. For a broader health overview, our borader Vitamin Test measures standard B12, folate, vitamins D, E, and CoQ10, ideal for those looking to address fatigue with a detailed nutrient profile.

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GetTested's Vitamin B12 test

GetTested's Vitamin B12 test is designed to accurately trace for B12 in the blood. 

Whereas traditional tests measure the total B12 in the body, encompassing both inactive and active forms, GetTested's Vitamin B12 test specifically measures holotranscobalamin, which is the active form of B12. This marker is more sensitive than MMA (methyl malonate), making it a reliable indicator of B12 deficiency. 

Measure your B12 levels with our vitamin b12 test kit, delivered to your door and convenient to use at home. If you suspect you may have a Vitamin B12 deficiency, test for B12 now and quickly gain insights into your health. 

About Vitamin B12

Vitamin B12, a crucial water-soluble vitamin, plays a vital role in our bodies. Unlike other vitamins, our body cannot produce B12, making dietary intake essential. There are two forms of Vitamin B12: an active form known as Active B12, bound to the protein transcobalamin, and an inactive form. Cells in the body utilise the active form.

One key function of B12 involves DNA production. Without B12, cells cannot divide properly, hindering the replacement of damaged or malfunctioning cells. B12 also contributes to nerve myelination (creating insulating fats around nerves) and breaks down homocysteine, a by-product of protein metabolism.

B12's Unique Absorption Process

Despite being water-soluble, B12 does not dissolve well in water or fat. Its absorption requires a special mechanism involving the intrinsic factor (IF), produced by stomach wall cells. This factor binds to B12, facilitating its transport through the intestinal wall, into the blood, and eventually to the liver. Here, it is stored or distributed throughout the body.

The liver can store B12 for up to 20 years. Unlike other B vitamins, regular B12 intake isn't necessary if liver reserves are sufficient. However, certain groups, including vegans, alcoholics, and individuals who have had bariatric surgery, face a higher risk of B12 deficiency. This risk arises from a potential reduction in intrinsic factor production, crucial for B12 absorption.

Symptoms of a B12 deficiency

A Vitamin B12 deficiency can cause a variety of symptoms that usually develop gradually. If untreated, these conditions can get worse.  

Most common symptoms of vitamin B12 include: 

  • Fatigue and weakness
  • Shortness of breath 
  • Stomach pain
  • Diarrhoea 

Vitamin B12 deficiency can also have an affect on mental well-being and cause:

  • Headaches,
  • Feelings of depression 
  • Anxiety 
  • Problems with memory

Symptoms of this deficiency range from mild (like fatigue and weakness) to more severe issues like heart palpitations, aforementioned mental health problems, and neurological symptoms. These symptoms may progress to pernicious anaemia or nerve-related issues like tingling, muscle weakness, and "burning feet syndrome," a result of inadequate myelin formation around nerves. 

Vegans and B12 Deficiency

Vitamin B12 naturally occurs in animal-based foods, placing vegans at a heightened risk of deficiency. For vegans, supplementing B12 is vital. The extent of deficiency largely depends on the liver's stored B12 levels at the time of switching to a vegan diet.


How is the Vitamin B12 test carried out?

Our Vitamin B12 test is a home test kit. After ordering, we will send you a kit with everything you need to collect the blood sample. Then, simply return your sample to us in the pre-paid envelope.

Who would benefit from testing their B12 levels?

Individuals who may benefit from testing their B12 levels include vegans and vegetarians, older adults, those with gastrointestinal disorders affecting nutrient absorption, and people who have had gastric surgery. Additionally, anyone experiencing symptoms like fatigue, weakness, memory problems, or neurological issues should consider a B12 test to rule out deficiencies.

What happens if I fail to take the sample?

If you read the instructions carefully before you take the test and it should go well. Should something go wrong, you are welcome to contact us and we will help you.

When should I take the test?

It is recommended to take the test on an empty stomach in the morning.

How quickly will I receive my results?

Once we receive your sample, average response time is 10-15 business days to receive results.

What is a Vitamin B12 test normal range?

A serum B12 above 300 pg/m is considered a normal range. If your B12 levels are below 200 pg/ml, you have a deficiency. Anything over 900 pg/m is considered too high and could indicate liver or kidney issues.

Deficiency of vitamin b12 can be diagnosed by which test?

The most reliable method to screen for a B12 deficiency is through a blood test. GetTested’s Vitamin B12 blood test measures the sensitive marker holotranscobalamin, which is an effective indicator of B12 deficiency.

What foods contain Vitamin B12?

Vitamin B12 is found in animal-based foods such as meat, fish, poultry, eggs and dairy products. Beef, liver, sardines, clams and dairy products in particular have a high level of Vitamin B12.

Example Report

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Example of Vitamin B12 Test


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  • Neil Morgan
    Revealed my deficiency. Feel revitalized post-adjustments.
  • Amelia
    nice! :)

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