About vitamin B12
Vitamin B12 plays an important role in our body and is an essential vitamin that belongs to the water-soluble vitamins. That it is essential means that the body cannot produce it itself and must be ingested through the diet. There are two different types of Vitamin 12, an active form (often called Active B12) and an inactive form. The active form, which is bound to the protein transcobalamin, is the one that the cells of the body can use.
One of the most important functions of B12 is the production of DNA. If the body cannot produce DNA, the cells cannot divide, which is necessary for broken and malfunctioning cells to be replaced with new ones. B12 is also needed for the myelination of the nerves (formation of special fats that insulate the nerves) and for the breakdown of homocysteine that is formed naturally during protein metabolism.
Standard tests today measure the total amount of B12 in the body, which includes both inactive and active B12. This vitamin B12 test measures holotranscobalamin, which is the active form of B12 in the body. Active B12 is a safe marker to detect if there is a B12 deficiency as it has a higher sensitivity than MMA (methyl malonate).
B12 – special absorption capacity
B12 belongs to the water-soluble vitamins but is not really soluble in water or fat-soluble substances. The uptake of B12 into the body requires a special mechanism, the so-called intrinsic factor (IF). Intrinsic factor is produced by cells in the wall of the stomach and acts as a carrier for B12 into the blood. Intrinsic factor attaches to B12 and is transported up through the intestinal wall, through the blood and to the liver where it’s either stored or transported to parts of the body that need the vitamin.
B12 is stored in the liver and can be stored there for up to 20 years. Unlike other B vitamins, the body does not need a regular supply of B12 if the depot is full due to the liver’s storage capacity. At the same time, it is important to remember that certain groups of people are at high risk for a deficiency of B12. In addition to vegans, alcoholics and people who have undergone bariatric surgery are also at high risk of developing B12 deficiency. The reason is that these groups may have a reduced production of intrinsic factor and without this, the body cannot absorb B12 in the gut.
Vegans and B12 – deficiency
Vitamin B12 is naturally present in foods of animal origin, which means that vegans are at high risk of developing a deficiency. Common symptoms are fatigue, weakness, pale skin, heart palpitations and mental problems like depression and memory loss. Severe deficiency can lead to pernicious anemia (special type of anemia), neurological symptoms that manifest themselves in the form of tingling and muscle weakness and which can also turn into a so called “burning feet syndrome” (this is du to that myelin cannot form and isolate the nerves properly). For vegans, B12 supplements are essential. How low the levels are in the body largely depends on the depots that were stored in the liver at the time of the change to a vegan diet.
Refunds and returns
General Terms and Conditions
GetTested offers a wide range of health analyses to individuals and companies. We collaborate with a number of subcontractors of medical laboratory operations for analysis of the samples. To order our analyses, you must be at least 18 years old, people under the age of 18 need a parent’s permit. GetTested is not a substitute for traditional healthcare. In case of any problems, you should always contact healthcare. When you place your order, you accept our terms of purchase.
You will receive your test result digitally via the login you created when you registered your test. The response time varies for different analyses, information on how long the response time your analysis takes can be found on the product page. You as a customer are responsible for registering your unique test ID in order to receive your analysis answer. Your analysis answers are sent encrypted with ID verification for maximum security.
Shipping and delivery terms
Shipping will be added with £ 4. Our products are sent to the address you specified when ordering. You as a customer are responsible for providing correct address information when ordering. If you have not received your delivery within 10 working days, please contact us at firstname.lastname@example.org and we will help you.
Prices and Payment
All prices are stated in GBP including VAT. Payment is made by card payment via the payment provider Stripe, which accepts VISA, Mastercard or AMEX.
Right of withdrawal
You as a customer have a 14-day right of withdrawal. The withdrawal period begins to apply on the day you received your goods. The right of withdrawal only applies to analyses that have not been sent to the laboratory for analysis and where the test kit, including the pre-stamped envelope, has not been used. Contact email@example.com to exercise your right of withdrawal and further instructions. If you do not return everything in original condition, we reserve the right to deduct the amount of the refund to cover the fees for the material cost. We ask you to follow the instructions carefully. If, contrary to expectation, you need more material to perform your test, you can buy it yourself in our online store. This is because we have pushed prices to the maximum so that you as a customer will receive the best offer on the market. In the event of a right of withdrawal, we will refund you within 30 days from the day you received the item. Any shipping and return costs are borne by the customer and are not refunded. If you as a customer have used your test kit and regret your purchase after that, we will charge a cost of £15 for the test kit and £4 for shipping (a total of £21) which is deducted from the total amount we refund you, this to cover the cost of the sample material.
If the item you received is damaged or if you received the wrong item, please contact firstname.lastname@example.org as soon as possible and we will help you. We ask you to follow the instructions carefully. Should you unexpectedly need more material to perform your test, please contact email@example.com. In the event of a dispute, we follow the General Complaints Board’s recommendations.
The personal information you provide in connection with your purchase is stored so that we can fulfil our agreement on services or products towards you. According to the Personal Data Act, you have the right to access the information we have registered about you. Contact us at firstname.lastname@example.org if any information is incorrect and we will correct it or delete it. If you have chosen to receive our newsletters, we will also process your personal data in order to send you information about our business.
GetTested reserves the right to make any price changes and is not responsible for any errors that may be attributable to a laboratory used for sampling and analysis. GetTested reserves the right to make errors in the article information.