Gut Microbiome Test Large

Test type
Lab Test

We offer two types of tests; Lab Tests and Rapid Tests. This product is under the category Lab Tests. See all our Lab Tests by following the link.

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Collection method

We offer several different options of testing methods. This test is done with Stool. See all tests done with Stool by following the link.

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GetTested’s Gut Microbiome Test Large is the test for you who want a comprehensive overview of your gut health. Many health problems arise from imbalances in our gut and this test is an in-depth analysis of your gut by measuring the presence of bacteria, yeast, the pH of the stool and digestive functions, such as pancreatic elastase, bile acids, digestive residues, as well as alpha-1 antitrypsin, calprotectin and secretory IgA.

If you’re dealing with IBS, consider combining this with our SIBO Test to further investigate potential root causes of your symptoms.

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Which items are measured in the Gut Microbiome Large test?

Escheria coli
Escherichia coli (E. coli) is a type of bacteria that is naturally found in the intestines of humans and other animals. It is a gram-negative, facultative anaerobic, rod-shaped bacterium that is a member of the Enterobacteriaceae family. E. coli is a beneficial bacteria that helps to break down food and produce vitamins. However, some strains of E. coli can cause food poisoning.
Escherichia coli Biovare
Escherichia coli Biovare, a distinct subspecies of E. coli, is unusual in the human intestine. It has several forms, including hemolytic, mucoid, and lactose-negative types. Finding hemolytic or mucoid E. coli is common, especially when there's an absence of beneficial E. coli and an alkaline pH level. Elevated levels of this subspecies can indicate inadequate mucosal immunity, often due to low production of secretory IgA.
Proteus is a genus of Gram-negative bacteria known for their ability to cause urinary tract infections (UTIs), particularly in people with long-term catheters or with a compromised immune system. They are also associated with wound infections and, less commonly, with respiratory system infections. Proteus bacteria are notable for their ability to resist multiple antibiotics, making infections challenging to treat.
Klebsiella is a genus of Gram-negative bacteria found in various environments, including soil, water, and the human gut. Some species, like Klebsiella pneumoniae, are significant pathogens, causing infections in the lungs (pneumonia), bloodstream, urinary tract, and wounds. Klebsiella bacteria are known for their antibiotic resistance, which complicates treatment options and is a major concern in healthcare settings.
Pseudomonas in stool can indicate an infection or overgrowth in the gastrointestinal tract. While not a common gut pathogen, Pseudomonas aeruginosa can cause problems, particularly in immunocompromised individuals. Its presence in stool may signal an imbalance in gut flora or a more serious underlying condition, especially when accompanied by gastrointestinal symptoms.
Enterobacter, a genus of common bacteria, can be found in the human gut. Typically harmless, they form part of the natural gut flora. However, in certain conditions, their overgrowth can indicate or cause health issues. Monitoring Enterobacter levels in stool can provide valuable insights into gut health and help diagnose various conditions.
Serratia, a type of bacteria often found in the environment, can also appear in the human intestinal tract. While it's generally harmless in healthy individuals, its presence in stool might be a concern for people with certain health conditions. Detecting Serratia in stool tests can indicate potential gut flora imbalances or infections.
Hafnia, a genus of bacteria typically found in the intestinal tract, is part of the normal gut flora. While generally harmless, its presence in stool can sometimes indicate digestive disturbances or an imbalance in gut microbiota.
Enterococcus, commonly found in the human intestines and part of the normal gut flora, plays a role in gut health. However, its overgrowth in stool can indicate an imbalance or potential infection, particularly in those with weakened immune systems.
Bifidobacterium is a crucial genus of bacteria that resides predominantly in the human gastrointestinal tract. These bacteria play a vital role in maintaining gut health, aiding in digestion, and boosting the immune system. They also help in the synthesis of essential vitamins and fighting harmful bacteria. A balanced presence of Bifidobacterium is key to a healthy gut microbiome.
Bacteroides spp. are a significant group of bacteria in the human gut microbiome. They play a vital role in breaking down complex carbohydrates and producing short-chain fatty acids, which are crucial for colon health. Bacteroides are also important for immune system regulation and protecting against harmful pathogens.
Lactobacillus is a beneficial bacteria commonly found in the gut and some fermented foods. It plays a crucial role in digestive health, aiding in nutrient absorption and supporting the immune system.
Clostridium refers to a genus of bacteria, some species of which are found naturally in the human gut, while others can cause illnesses. These bacteria can survive in harsh conditions due to their ability to form spores. While certain Clostridium species play a role in gut health, others, like Clostridium difficile, can lead to severe infections, especially after antibiotic use that disrupts the normal gut flora.
Candida spp
Candida spp includes various yeast-like fungi affecting body parts like the gut and vagina. These infections often cause itching, discomfort, and discharge. They result from flora imbalance. In the gut, Candida spp can disrupt digestion. This leads to bloating and changes in bowel habits. Diet, health, and antibiotics are contributing factors. Addressing these is crucial to restore balance and relieve symptoms.
Candida albicans
Candida albicans is a type of yeast that can affect various parts of the body, most commonly manifesting as vaginal yeast infections and gut overgrowth. Vaginal infections bring itching, discomfort, and discharge, often due to flora imbalance. In the gut, overgrown Candida albicans disrupts digestion, causing bloating and bowel habit changes. Diet, health, and antibiotics influence both conditions, requiring tailored treatments to restore balance and relieve symptoms.
Yeast, a type of fungus, is commonly found in the human body, especially in the gut and on the skin. In small amounts, it's harmless. However, imbalances can lead to overgrowth, causing various health issues. Factors like diet, antibiotics, and overall health influence yeast levels.
Geotrichum candidum
Geotrichum candidum is a type of fungus often found in soil, water, air, and some food products. In the human body, it's commonly present in the gut and on the skin. While typically harmless, Geotrichum candidum can cause issues in immunocompromised individuals.
pH value
The pH value of the stool can indicate if there are any conditions of excess decay or fermentation in the intestine. A too low pH value often occurs in combination with a dysfunctional intestinal flora, as complex sugars are metabolized to fatty acids, which can contribute to an acidified stool. A too high pH value can be due to excessive amounts of protein, which can stimulate certain intestinal bacteria to produce ammonia and other metabolic products, thus raising the pH value of the stool.
Pancreatic elastase
Pancreatic elastase is an enzyme produced by the pancreas, crucial for digesting proteins. Measuring its levels in feces provides valuable information about pancreatic function. This enzyme remains stable in fecal matter, making it a reliable indicator for evaluating the exocrine function of the pancreas, particularly in diagnosing conditions like pancreatic insufficiency.
Bile acids
Bile acids, essential for digesting fats, are produced in the liver and stored in the gallbladder. Normally, they are reabsorbed into the body, but a portion ends up in stool. Analyzing bile acids in stool can help understand digestive health, especially in diagnosing malabsorption issues.
Calprotectin, a protein in white blood cells, indicates inflammation, especially in the gut. Testing calprotectin in feces shows how inflamed the intestines are. This helps diagnose and track inflammatory bowel diseases like Crohn's and ulcerative colitis. It also helps distinguish these from irritable bowel syndrome (IBS), which usually doesn't raise calprotectin levels.
Alpha-1 antitrypsin
Alpha-1 antitrypsin (AAT) is a protein primarily produced by the liver, playing a key role in protecting the lungs and other organs from enzymes that can cause inflammation. In feces, measuring alpha-1 antitrypsin can help assess intestinal protein loss and inflammation, indicating gastrointestinal disorders like inflammatory bowel disease or protein-losing enteropathy.
Secretory IgA
Secretory IgA (Immunoglobulin A) is a critical component of the immune system, primarily found in mucosal areas like the intestines, respiratory tract, and saliva. It plays a key role in the body's first line of defense, protecting mucosal surfaces by binding to pathogens and preventing their entry into the body. Secretory IgA is essential for maintaining gut health and overall immune function.
Quantitative Determination of Fat
The quantitative determination of fat in stool samples, often referred to under the umbrella of digestive residues, is a diagnostic test used to evaluate fat absorption and to identify malabsorption syndromes. This test, measures the amount of fat that is excreted in the stool. Excessive fat in the stool, a condition known as steatorrhea, can indicate problems with digestion or absorption of fat in the gastrointestinal tract. The results of this test help in diagnosing conditions such as pancreatic insufficiency, cystic fibrosis, celiac disease, and Crohn's disease.
Quantitative Determination of Nitrogen
The quantitative determination of nitrogen is a laboratory test primarily used to assess protein digestion and absorption by measuring nitrogen levels in bodily excretions, usually urine or feces. This test is instrumental in evaluating nutritional status, particularly in clinical settings where protein-energy malnutrition or imbalances might be a concern. It serves as a key indicator of metabolic functions related to protein turnover. The test can help diagnose conditions that affect protein metabolism, such as kidney disease, malabsorption syndromes, and certain metabolic disorders.
Quantitative Determination of Sugar
The quantitative determination of sugar in stool is a diagnostic test used primarily to detect carbohydrate malabsorption. This type of test is valuable for diagnosing conditions such as lactose intolerance, fructose intolerance, and other disorders where the digestion and absorption of sugars are impaired. By measuring the levels of sugars such as lactose, fructose, or sorbitol in the stool, healthcare providers can identify the specific sugars that a patient's digestive system cannot process effectively. The presence of undigested sugars in the stool often leads to symptoms such as bloating, gas, diarrhea, and abdominal pain.
Quantitative Determination of Water
The quantitative determination of water in stool, commonly referred to as stool water content analysis, is a diagnostic test used to evaluate the water content in feces. This test is crucial for diagnosing conditions associated with abnormal water absorption or secretion in the gastrointestinal tract, such as various forms of diarrhea. Diarrhea can result from infections, inflammatory bowel diseases (IBD), irritable bowel syndrome (IBS), or malabsorption syndromes, where there is either excessive secretion or inadequate absorption of water in the intestines.

Gut Microbiome Test Large: Detailed Gut Health Assessment

The Gut Microbiome Test Large from GetTested is a thorough test that evaluates key aspects of gut health. It measures digestive functions, digestive residues, and the levels of various bacteria and yeasts in the intestinal flora. Additionally, it assesses digestive malabsorption and inflammatory markers. This test aims to provide a comprehensive understanding of your digestive system and gut flora health.

Who Would Benefit from the Gut Microbiome Test Large?

Individuals with digestive issues, such as imbalances in gut flora, candida overgrowth, or food digestion difficulties, will find this test particularly beneficial. It offers an in-depth analysis of potential gut imbalances and can aid in preventing future health problems.

Components of the Gut Microbiome Test Large

This comprehensive test encompasses:

  • Evaluations of 13 types of gut bacteria, like Bifidobacterium and Lactobacillus.
  • Analyses of 4 yeast types, including Candida albicans and Geotrichum candidum.
  • pH value assessments.
  • Digestive residue checks for fat, nitrogen, sugar, and water.
  • Measurements of secretory IgA, pancreatic elastase, bile acids, alpha-1 antitrypsin, and calprotectin.

Understanding Yeast Overgrowth

The test also focuses on Candida albicans, a yeast that, in moderate amounts, aids digestion and nutrient absorption but can cause health issues if overgrown. Factors such as antibiotics, diet, heavy metal poisoning, and certain medications can lead to yeast overgrowth. Thus, the test includes analysis of Candida spp., Geotrichum candidum, and general yeast levels.

How to Perform the Gut Microbiome Test Large

This stool test is conveniently conducted at home. The test kit includes all necessary materials. After collection, the sample is sent to our ISO-certified lab for analysis. You'll receive your results digitally, offering a comprehensive view of your gut health.

For Leaky Gut Assessment

Additionally, for those seeking an in-depth analysis including leaky gut indicators, we recommend the Gut Microbiome Test XL. This advanced version extends the Large test's capabilities by also measuring zonulin and histamine.


How is the Gut Microbiome test Large carried out?

Our Gut Microbiome test Large is a home test kit. After ordering, we will send you a kit with everything you need to collect the stool samples (2 tubes). Then, simply return your sample to us in the pre-paid envelope.

Who should get a Gut Microbiome test Large?

Individuals who should consider getting the Gut Microbiome Test Large typically include those experiencing chronic digestive issues such as bloating, irregular bowel movements, and abdominal discomfort. It's also beneficial for individuals suspecting gut flora imbalances, candida overgrowth, or food digestion difficulties. Additionally, people with conditions potentially linked to gut health, like allergies, autoimmune diseases, or chronic fatigue, might find this test insightful. The test is also suitable for those who have undergone extensive antibiotic treatments and wish to assess the impact on their gut microbiome, as well as for anyone interested in a comprehensive evaluation to optimize their overall gut health and well-being.

How quickly will I receive my results?

Once we receive your sample, average response time is 10-15 business days to receive results.

Anything to consider before taking the test?

Avoid probiotics at least 72 hours before the test and antibiotics 2-4 weeks before the test.

Example Report

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Example of Gut Microbiome Test Large


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  • Farah Malik
    Having experienced unexplained digestive issues for years, I had almost accepted it as my norm. However, the Gut Microbiome Test (Large) by GetTested seemed like a comprehensive solution worth exploring. Right from the start, the kit’s delivery was prompt and the instructions provided were crystal clear. Taking the sample was a straightforward process, devoid of any complications. When the results rolled in, it was a revelation. The detailed insights into the diverse bacterial population in my gut and their relative proportions provided a clearer picture of my digestive landscape. The specifics about each bacteria, its role, and implications on health were particularly enlightening. Since getting the results, I've worked closely with my nutritionist to make adjustments to my diet, focusing on fostering a healthier gut environment. The difference has been undeniable. My digestion has improved, and the once frequent bloating episodes are now rare occurrences. For anyone grappling with similar issues, this test is a valuable resource in the journey to better gut health.
  • Sophia Grant
    Navigating my health journey has always been a challenge, especially with the recurrent digestive issues I faced. I had heard of microbiome testing but had reservations about its efficacy until I decided to finally take the plunge. The anticipation grew from the moment the kit arrived. Every step, from collection to sending the sample, was methodically laid out, making the entire process feel professional and streamlined. My scepticism was further put to the test as I awaited the results, hoping for answers that eluded me for years. When the comprehensive report finally landed in my inbox, it was like deciphering a personal code. Each segment of the data unraveled a story about the tiny inhabitants of my gut and their substantial impact on my overall health. The detailed breakdown of bacteria strains, their concentrations, and associated functions were presented with such clarity that it was impossible not to be intrigued. Armed with this newfound understanding, I sought guidance from a nutrition expert. Together, we embarked on a mission to rectify the imbalances, leveraging the insights from the report. The following months were transformative. Not only did my digestive discomforts diminish, but there was also a notable improvement in my energy levels and mood. In reflection, delving deep into the world of my gut’s microbiome was an enlightening experience. For anyone on the fence about such testing, I can vouch for its potential to pave the way for a more informed and healthier life.

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