Alanine aminotransferase (ALT), formerly known as serum glutamic-pyruvic transaminase (SGPT), is an enzyme primarily found in the liver. It plays a vital role in metabolizing proteins and is crucial for various metabolic processes. ALT levels in the blood are indicative of liver health, as the enzyme is released into the bloodstream when liver cells are damaged or inflamed....


Who would benefit from testing their ALT (SGPT) value?

  • Individuals exhibiting symptoms of liver disease (jaundice, fatigue, abdominal pain).
  • Patients with conditions known to affect liver health, such as hepatitis or fatty liver disease.
  • Those taking medications with potential liver toxicity.
  • People with a history of alcohol abuse or other risk factors for liver damage.
  • Individuals undergoing routine health check-ups, as ALT testing is a standard component of liver function tests.

What are the common symptoms of too high ALT (SGPT) values?

  • Fatigue and weakness
  • Abdominal pain or discomfort
  • Jaundice (yellowing of the skin and eyes)
  • Itchy skin
  • Dark urine
  • Nausea or loss of appetite

What can cause too high ALT (SGPT) values in blood?

High ALT levels typically indicate liver damage or inflammation. Causes can include:

  • Viral hepatitis (hepatitis A, B, C)
  • Alcohol-related liver disease
  • Non-alcoholic fatty liver disease
  • Cirrhosis
  • Liver cancer
  • Exposure to toxins or medications that affect the liver

What can I do to improve ALT (SGPT)?

  • Reduce alcohol consumption or abstain completely.
  • Maintain a healthy weight and follow a balanced diet.
  • Exercise regularly to help manage body weight and improve liver health.
  • Avoid unnecessary medications or supplements that could stress the liver.
  • Control blood sugar levels and manage conditions like diabetes and cholesterol.
  • Seek medical treatment for any underlying liver conditions.
  • Regularly monitor liver health through medical check-ups.

Test(s) that measure/test for ALT (SGPT)

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