CHRM2 (Cholinergic Receptor Muscarinic 2): CHRM2 is a G protein-coupled receptor (GPCR) that plays a vital role in the modulation of parasympathetic nervous system activity, specifically in heart rate regulation and cognitive functions. It mediates the effects of acetylcholine, a key neurotransmitter in both the central and peripheral nervous systems, on various physiological processes. Activation of CHRM2 leads to a decrease in heart rate and cardiac contraction strength, making it crucial for the cardiac response to the vagus nerve stimulation. In the brain, CHRM2 is involved in learning, memory, and neuroplasticity, indicating its importance in cognitive functions and potential as a therapeutic target for neurological disorders. Dysregulation of CHRM2 has been associated with various pathologies, including heart diseases, Alzheimer's disease, and psychiatric disorders, underscoring its significance in maintaining cardiovascular and cognitive health.


Test(s) that measure/test for CHRM2

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