H2BC5 (Histone Cluster 2, H2bc5): H2BC5 is a member of the histone H2B family, which comprises proteins that play essential roles in packaging and organizing DNA within the nucleus of eukaryotic cells. Histone proteins, including H2BC5, form complexes with DNA to create chromatin, the structural unit of chromosomes. Within chromatin, histones undergo various post-translational modifications that regulate gene expression, DNA replication, and repair. H2BC5 is specifically involved in the formation of nucleosomes, which are the basic repeating units of chromatin structure. Nucleosomes consist of DNA wrapped around a core of histone proteins, including H2BC5. These nucleosomes can undergo dynamic changes in structure and composition to allow access to DNA for processes such as transcription, DNA replication, and repair. Dysregulation of histone proteins, including H2BC5, has been implicated in various diseases, including cancer and developmental disorders. Understanding the role of H2BC5 in chromatin organization and gene regulation is essential for elucidating the molecular mechanisms underlying these diseases and for developing potential therapeutic interventions targeting histone proteins. Further research into the function and regulation of H2BC5 may provide valuable insights into its role in health and disease.


Test(s) that measure/test for H2BC5

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