IFIH1

IFIH1 (Interferon Induced With Helicase C Domain 1): IFIH1, also known as MDA5, is an intracellular sensor of viral RNA. It plays a critical role in the innate immune defense against RNA viruses by recognizing viral replication and initiating an immune response. Mutations in IFIH1 have been associated with autoimmune disorders such as type I diabetes and systemic lupus erythematosus.

IFIH1

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