KLF6

KLF6, or Krüppel-Like Factor 6, is a transcription factor that belongs to the Krüppel-like family of zinc finger proteins. It plays crucial roles in the regulation of gene expression, cell proliferation, differentiation, apoptosis, and various biological processes involved in development, tissue homeostasis, and disease pathogenesis. One of the primary functions of KLF6 is its role as a transcriptional regulator. It binds to specific DNA sequences within the regulatory regions of target genes, known as Krüppel-like factor binding sites, thereby modulating their transcriptional activity. KLF6 can act as both a transcriptional activator and a repressor, depending on the cellular context and the...