LPCAT2

LPCAT2, also known as Lysophosphatidylcholine Acyltransferase 2, is an enzyme crucial for the biosynthesis of phospholipids, essential components of cellular membranes. Positioned primarily within the endoplasmic reticulum of cells, LPCAT2 plays a pivotal role in regulating lipid metabolism and maintaining membrane integrity. One of the key functions of LPCAT2 is its involvement in the Lands cycle, a process essential for the remodeling of phospholipids. LPCAT2 catalyzes the acylation of lysophosphatidylcholine (LPC) molecules, converting them into phosphatidylcholine (PC), a major phospholipid constituent of cell membranes. This enzymatic activity is crucial for generating membrane phospholipids with specific fatty acid compositions, which influence membrane...