MCFD2

MCFD2 (Multiple Coagulation Factor Deficiency 2): MCFD2 is a key component of the complex responsible for the transport and proper folding of coagulation factors V and VIII, which are essential for blood clotting. Mutations in MCFD2 cause combined factor V and VIII deficiency, a rare bleeding disorder. This highlights the critical role of protein transport and folding mechanisms in hemostasis and the impact of their dysregulation on blood clotting disorders....