MICB (MHC Class I Polypeptide-Related Sequence B): MICB is a stress-induced ligand for the NKG2D receptor, which is expressed on the surface of natural killer (NK) cells, CD8+ T-cells, and certain γδ T-cells. The interaction between MICB and NKG2D plays a crucial role in the immune surveillance against malignant and infected cells. Upregulation of MICB on stressed, transformed, or infected cells can trigger an immune response leading to cell lysis. Therefore, MICB is important for immune defense against cancer and viral infections....


Test(s) that measure/test for MICB

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