PRDM6 (PR Domain Containing 6): PRDM6 is a member of the PRDM family of transcriptional regulators, known for its role in epigenetic modifications and gene expression regulation. It acts primarily as a transcriptional repressor, influencing the development and function of cardiovascular and other systems by modulating the expression of genes involved in cell differentiation, proliferation, and apoptosis. PRDM6 is particularly important in vascular development and smooth muscle cell differentiation, where its precise regulation is crucial for normal blood vessel formation and cardiovascular homeostasis. Dysregulation of PRDM6 has been implicated in various pathological conditions, including hypertension, vascular remodeling, and potentially contributing to the progression of cardiovascular diseases. Its function in gene silencing and activation through histone modifications underlines its importance in cellular and developmental biology, making PRDM6 a potential target for therapeutic interventions in diseases related to vascular abnormalities and beyond.


Test(s) that measure/test for PRDM6

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