RNF220

RNF220 (Ring Finger Protein 220): RNF220 is a member of the RING finger proteins, characterized by their specialized zinc finger domain that confers E3 ubiquitin ligase activity. This protein plays a critical role in the ubiquitin-proteasome system, a cellular mechanism responsible for protein degradation and turnover. Through its E3 ligase function, RNF220 is involved in targeting specific substrates for ubiquitination, thereby regulating their stability and activity within the cell. This regulation is essential for maintaining cellular homeostasis and responding to stress and damage signals. The activity of RNF220 is pivotal in various cellular processes, including signal transduction, DNA repair, and...

RNF220

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