ZFPM1

ZFPM1 (Zinc Finger Protein, FOG Family Member 1): ZFPM1, also known as FOG-1, is a cofactor that interacts with GATA family transcription factors, playing a crucial role in the development and differentiation of various cell types, including those in the heart and blood. It is particularly important for erythroid and megakaryocyte differentiation. Mutations or dysregulation of ZFPM1 can affect hematopoiesis, leading to blood disorders. Additionally, ZFPM1's involvement in cardiac development implicates it in congenital heart defects. Research on ZFPM1 focuses on understanding its role in the intricate network of gene regulation governing cell fate decisions, with implications for treating related...